Hyaluronic acid serum is one of the most effective and popular skincare products for deep hydration, plumping, and improving skin texture. The best part? You can make a high-quality serum at home using just a few simple ingredients.
In this guide, we’ll walk you through exactly how to create your own DIY hyaluronic acid serum from scratch, using professional-grade raw ingredients.
Why Make Your Own Hyaluronic Serum?
Making your own serum gives you:
- Full control over ingredients
- No unnecessary fillers or fragrances
- Cost savings (especially if you make batches)
- The ability to customize for your skin
Plus, when you use high-quality hyaluronic acid, you can achieve results comparable to premium store-bought products.
Choosing the Right Hyaluronic Acid Powder
Not all hyaluronic acid is the same.
We recommend using a high molecular weight hyaluronic acid, which sits on the surface of the skin and provides:
- Superior hydration
- A smooth, plumping effect
- Reduced moisture loss
👉 You can use our high molecular weight hyaluronic powder here:
https://shopbrooksie.com/products/hyaluronic-powder
This is ideal for DIY serums and beginner-friendly formulations.
DIY Hyaluronic Acid Serum Recipe (2 oz Batch)
Here’s a simple, balanced formula based on a professional-grade recipe.
Ingredients (2 oz / ~56.7g total)
- Distilled Water – 54.5g (≈ 96%)
- Aloe Vera Liquid – 1.0g (≈ 1.7%)
- Vegetable Glycerin – 0.85g (≈ 1.5%)
- Hyaluronic Acid Powder – 0.57g (1.0%)
- DL-Panthenol (Provitamin B5) – 0.14g (≈ 0.25%)
- Liquid Germall Plus (preservative) – 0.06g (0.1%)
Equipment You’ll Need
- Digital scale (accurate to 0.01g recommended)
- Mixing bowl or beaker
- Stirring tool or mini whisk
- Sanitized 2 oz bottle (pump or dropper)
- Gloves (optional but recommended)
Step-by-Step Instructions
1. Sanitize Everything
Clean all tools, containers, and your workspace. This is critical since your serum contains water and needs to stay safe from bacteria.
2. Mix Water + Hydration Base
In a clean container, combine:
- Distilled water
- Aloe vera liquid
- Glycerin
Stir until fully blended.
3. Slowly Add Hyaluronic Acid Powder
This is the most important step.
- Slowly sprinkle the hyaluronic acid powder into the liquid
- Do NOT dump it all at once (it will clump)
Let it sit for 30–60 minutes, then gently mix again.
👉 The mixture will thicken into a gel as it hydrates.
4. Add Active Ingredients
Once the gel has formed:
- Add DL-Panthenol
- Add Liquid Germall Plus
Mix thoroughly.
5. Bottle Your Serum
Transfer the finished serum into your sanitized 2 oz container.
How to Use Your Serum
Apply a small amount to slightly damp skin:
- Morning and/or night
- Follow with a moisturizer to lock in hydration
Shelf Life & Storage
Because this is a water-based product:
- Use within 8–12 months
- Store in a cool, dry place
- Always include a preservative (like in this recipe)
Want an Easier Option?
If you’d rather skip the mixing and go straight to filling and customizing:
👉 Check out our ready-to-use Hyaluronic Serum Base:
https://shopbrooksie.com/products/hyaluronic-serum-base
It’s perfect for:
- Small businesses
- DIY skincare brands
- Anyone who wants a shortcut without sacrificing quality
Final Thoughts
Making your own hyaluronic acid serum is surprisingly simple—and incredibly rewarding. With just a few ingredients, you can create a clean, effective product tailored exactly to your needs.
If you're getting started, the most important factor is using a high-quality hyaluronic acid powder, like our high molecular weight option, to ensure the best hydration and skin feel.